Case Report: Longitudinal monitoring of clonal evolution by circulating tumor DNA for resistance to anti-EGFR antibody in a case of metastatic colorectal cancer

BackgroundTreatment with anti-EGFR antibody has Vitamins C been shown to prolong survival in patients with RAS wild-type metastatic colorectal cancer (mCRC).However, even patients who initially respond to anti-EGFR antibody therapy, almost without exception, develop resistance to the therapy and then fail to respond.Secondary mutations in the mitog

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New lexical blends in The Simpsons: a formal analysis of English nonce formations and their French translations

This contribution examines the conspicuous presence of lexical blends in the long-running US television show The Simpsons and consists of two parts.The first part involves the formal analysis of 237 nonce blends in the original English-language version of the show, working on the underlying hypothesis that, despite their novelty, the audience is no

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