This review article summarizes the role of heterocyclic compounds as anticancer drugs used against various human cancers, including doxorubicin, cisplatin, paclitaxel, and resveratrol, which are among the most effective therapeutic agents.Chemotherapy, a treatment modality, exerts its effects on tumor cell DNA and often involves the use of low-mole
Case Report: Longitudinal monitoring of clonal evolution by circulating tumor DNA for resistance to anti-EGFR antibody in a case of metastatic colorectal cancer
BackgroundTreatment with anti-EGFR antibody has Vitamins C been shown to prolong survival in patients with RAS wild-type metastatic colorectal cancer (mCRC).However, even patients who initially respond to anti-EGFR antibody therapy, almost without exception, develop resistance to the therapy and then fail to respond.Secondary mutations in the mitog
Suboptimal Approach to Distributed Detection in Cognitive Radio Networks
In this paper a dynamic spectrum access (DSA) concept is explored for mitigating Bosch Serie 4 DWK97HM60B Angled Chimney Cooker Hood the paucity of spectral bandwidth in cognitive radio (CR) for opportunistic, dynamic access of the spectrum without any interference.Dynamic spectrum access schemes are proposed for a distributed cognitive radio netwo
Metabolic effects of prolactin and the role of dopamine agonists: A review
Prolactin is a polypeptide hormone that is well known for its role in reproductive physiology.Recent studies highlight its role in neurohormonal appetite regulation and metabolism.Elevated prolactin levels are widely associated with worsening metabolic disease, but it Left Handrail appears that low prolactin levels could also be metabolically unfav
New lexical blends in The Simpsons: a formal analysis of English nonce formations and their French translations
This contribution examines the conspicuous presence of lexical blends in the long-running US television show The Simpsons and consists of two parts.The first part involves the formal analysis of 237 nonce blends in the original English-language version of the show, working on the underlying hypothesis that, despite their novelty, the audience is no